Ring around the Ro-sie: RNA-Mediated Alterations of PNPase Activity
نویسندگان
چکیده
Chen et al. demonstrate a new way by which noncoding RNAs tailor the function of multicomponent complexes. They show that a noncoding RNA interacts with an exoribonuclease, altering its substrate specificity and enzymatic activity by serving as a ribonucleoprotein scaffold and, perhaps, a gate for entry of the RNA substrate.
منابع مشابه
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ورودعنوان ژورنال:
- Cell
دوره 153 شماره
صفحات -
تاریخ انتشار 2013